Also, there aren’t any standards for making supplements, so you might find products with different recommendations and doses and unclear labels. A single unit of plant-based DAO has a gigantic catalytic power compared to the same unit of animal-based DAO. Beyond this, of course, there are other positive and decisive factors to choose plant-based DAO, such as its ‘cruelty-free’ origin (the animal-based one usually comes from pig kidneys) and the fact that it’s a product of plant origin, making it a 100% suitable supplement for vegans.

Cellulose (vegetable origin), LEGUMACTIVE® (peas *Pisum sativum, lentils * Lens Culinaris), hydroxypropylcellulose (vegetable origin), stearic acid (plant origin) and silicon dioxide (mineral origin). This resource is not a substitute for your doctor or other healthcare professionals, and is designed to increase your knowledge and understanding of your healthcare options. It’s important to consider that the DAO supplement should go before the meal, as its content will serve to break down those amines to prevent them from being absorbed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by Breakspear Medical.International Journal of Immunopathology and Pharmacology: “Serum diamine oxidase activity in patients with histamine intolerance. Coming from the membranes of our legumes, catalase plays an important role in how the DAO enzyme works. By taking Naturdao Plus, you will help your body deal with excess histamine and the symptoms of DAO deficiency , adding essential nutrients to improve the activity of endogenous DAO in its activated format. People with histamine intolerance who took DAO supplements showed improvement in at least one digestive symptom. In the case of DAO, it’s HDU (Histamine Digesting Units), which comes from the abbreviation in English: Histamine Digesting Units.

Naturdao is a food supplement recommended for people with DAO deficiency, that is, diamine oxidase deficiency. If the symptoms subside when dieting, we can say that there is histamine intolerance and take the next step, which is to look for and analyze the main reason for this intolerance so as to find the root cause. So, yesterday I received my diamine oxidase supplements and today, I took one pill, five minutes before pizza, and then I ate some pizza. In other words, this vast difference in enzymatic activity indicates that plant-based DAO in the digestive tract can break down hundreds of times more amines from ingested food in fractions of a second.This same enzyme, histaminase or diamine oxidase (DAO), present in the small intestine and ascending colon (and kidney), breaks down ingested histamine and normally prevents its passage to plasma in significant amounts (Kovacova 2015, Kanny 1999). These cookies allow us to count visits and traffic sources so that we can measure and improve the performance of our site. International Archives of Allergy and Immunology: “Diamine Oxidase Supplementation in Chronic Spontaneous Urticaria: A Randomized, Double-Blind Placebo-Controlled Study. However, some studies found that a low-histamine diet didn’t change the enzyme activity in the body.

I’ve become so reactive to histamine that I have to take 4 antihistamines a day and a dao tablet with every meal. The information provided on this page does not constitute advice and should not be taken over the advice of medical practitioners, pharmacists, or any other licensed healthcare professionals. Furthermore, from the 7th month of pregnancy, your placenta will produce about 500 times more DAO than usual as a mechanism to protect the fetus. For its effectiveness, it is highly recommended to follow a program tailored to your needs by a dietician, nutritionist or professional with knowledge of the field.We do our best as science loving, evidence-based health practitioners to provide accurate, up-to-date information, but we cannot replace your real-life health professionals. Desde que lo descubrí, es lo mejor que he encontrado para controlar la histamina, los brotes que padezco hace unos años y los medicos no tienen ni idea del porqué, solo saben dar corticoides. Regarding stability, both, over time, without being presented in a specific galenic format, inevitably denature, gradually losing their enzymatic activity.

It is important not to follow the diet indefinitely and not without the supervision of a qualified nutritionist. The catalase enzyme (CAT) provides oxygen by favouring the balance to decompose the DAO-histamine reaction. Studies from human intestinal cells suggest that when histamine degrades via DAO, toxic compounds are released such as hydrogen peroxide, ammonia and imidazole acetaldehyde; however, with the presence of CAT this does not happen. So, your natural ability to degrade histamine will increase substantially, and mostly, you will not require DAO supplementation. In addition, it naturally contains the enzyme catalase, which favors the decomposition of DAO_Histamine.

Thanks to its potent DAO enzyme contribution, it boasts the highest enzymatic activity among DAO supplements. The information generally does not directly identify you, but it can provide you with a more personalized web experience. Legumactive based food supplement, which is a 100% natural method made of organic selection legumes, offers a powerful enzymatic activity of DAO (Diamino Oxidase) and Catalase together with its Phytonutrients. NaturDAO’s high activity is over 700 times higher than other DAOs of animal origin, while being completely vegan.